09-09-2019, 12:25 AM
Mother Nature is trying to rid this planet of humans like a dog shaking off fleas. Let us not interfere with her good works.
miley-gen013:

Reversing aging might be possible
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09-09-2019, 12:25 AM
Mother Nature is trying to rid this planet of humans like a dog shaking off fleas. Let us not interfere with her good works.
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09-09-2019, 12:35 AM
Yoyodyne ArtWorks wrote: :facepalm:
09-09-2019, 12:52 AM
Sooooooo.....isn't this how we end up with Zombies?
09-09-2019, 01:38 AM
Newsweek did not even followup.
The Nature citation is a news article. https://www.nature.com/articles/d41586-019-02638-w The main paper can be accessed here: https://www.gwern.net/docs/longevity/2019-fahy.pdf None of the links in the Nature article seemed to work for me, so I thought I'd post. This paper is quite preliminary in my opinion - including the idea that there is an 'epigenetic clock' is controversial.
09-09-2019, 11:05 AM
....can you reverse Age of Innocence......???
09-09-2019, 12:36 PM
From what I've read, the idea behind using methyl as a proxy for aging is that it accumulates over time and supposedly interferes with gene-expression and transcription. Whether it is a reliable indicator of age or infirmity is still up for debate.
I think it's similar to the shortening telomeres thing. Seemed to be a good way to estimate a subject's age, but clones end up with shorter telomeres than otherwise and often live normal-length lives, so it's more complicated than just the length of telomeres. Correlation does not equal causation and all that... Seems that there are lots of other factors: Accumulating DNA damage, fewer stem cells, viral infection (seems that common viruses have surprising influences on brain-function over time)... And general wear-and-tear. Any geneticists in the forum who care to comment?
09-09-2019, 01:48 PM
I don’t know about reversing aging, but I think drug (or gene) therapies slowing aging (already being done in experimental animals) may not be as many as 30 years away.
09-09-2019, 01:56 PM
....so we can 'Benjamin Button'.....this sucker....???
09-09-2019, 03:53 PM
No controls.
No researcher blinding. Uses a proxy for actual effects. This is the thinnest of preliminary data but at least it suggests obvious experiments to generate actual data.
09-09-2019, 03:59 PM
....if I could turn back time.....if I could find....a way.....
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